Ajmalan-17,21-diol, (17R,20α,21β)- - Names and Identifiers
Ajmalan-17,21-diol, (17R,20α,21β)- - Physico-chemical Properties
Molecular Formula | C20H26N2O2
|
Molar Mass | 326.44 |
Melting Point | 23l-3°C (dec.). |
Appearance | Powder |
Storage Condition | 2-8℃ |
Ajmalan-17,21-diol, (17R,20α,21β)- - Introduction
()-Isoajmaline, chemical name ()-Isoajmaline, is an alkaloid compound. It is a typical product of the above reaction, that is, in this reaction, the thiolamine (thiolamine) and the haloalkene (haloalkene) nucleophilic substitution reaction, under the condition of strong alkaline stable intervariant structure alkali salt (quaternary salt), the nature is white crystalline solid. Ionic nitrogen must be asymmetric nitrogen, which has Optical rotation: [α]25/D 256, c = 0.79 in methanol
( )-Isoajmaline has antiarrhythmic activity in medicine and can also be used as a synthetic raw material for alkaloids. In addition, it has antihypertensive, hypolipidemic, anti-inflammatory and other pharmacological effects.
The method of preparing ()-Isoajmaline can be obtained from natural sources, such as extraction from Rauwolfia (Rauwolfia serpentina). It can also be obtained by chemical synthesis.
Regarding safety information,( )-Isoajmaline should be operated in a professional laboratory environment, follow safe operating procedures, and wear appropriate protective equipment. It can be toxic to humans and can cause irritation and allergic reactions, so precautions should be taken to avoid inhalation, contact with skin and eyes. If inhaled or exposed, wash immediately and seek medical help.
Last Update:2024-04-09 20:49:11